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As expected, the addition of the dimeric macrocycles produced a slower migrating band compared with the band of monomeric Met, indicating that the cross-linked Met dimer was formed (Fig

This is driven by the likelihood of subchondral bone changes as a consequence of failed repair, particularly if the first attempt involved disruption of the tidemark for marrow recruitment

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ECs forming tumor vessels are loosely connected with each other and have an irregular morphology

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DSIP can be administered via subcutaneous injection or nasal spray, with the choice of administration method influenced by factors such as ease of use and expected effects
