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Accessed July 10, 2014

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Most studies have used tractable, transformed cell models, such as HeLa and 293T, which rapidly respond to amino acid withdrawal by down-regulating mTORC1 signaling, thereby halting anabolic growth

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One key gene is BCL2, which promotes cell survival

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Further research into the uses of BOTOX led to patients noting that their wrinkles were smoother after treatment

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