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Desde entonces, se ha estudiado en animales para evaluar su potencial en la reparacin de tejidos, la reduccin de la inflamacin y la aceleracin de la cicatrizacin

doi:10.1002/psc.70016

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When TLR4 is activated by bacterial LPS or by molecules from injured cells, it triggers a cascade of events that causes the cell to produce inflammatory cytokines.[ref] LDN is thought to block the activation of TLR4, thus reducing the release of inflammatory cytokines such as TNF-alpha, IL-6, and IL-12.[ref] LDN is one of the few TLR4 antagonists that can cross the blood-brain barrier.[ref] An animal study of multiple sclerosis found that naltrexone prevents the learning and memory issues associated with neuroinflammation