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Furthermore, its reactions with one-electron oxidants are faster than similar reactions of thiols [107]

Given that many PD-associated proteins regulate mitochondrial health, oxidative stress, and iron homeostasis, their dysregulation provides a direct mechanistic bridge to ferroptosis in PD progression ( Figure 3 )

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Geotimes 46(1):2427 Prospero JM, Bullard JE, Hodgkins R (2012) high-altitude dust over the north Atlantic: inputs from Icelandic proglacial dust storms