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doi: 10.1038/cr.2009.139

View in: PubMed Mentions: 3 Fields: Translation:Humans A randomized controlled trial of methylergonovine prophylaxis after dilation and evacuation abortion

Its working mechanism is allosteric facilitation of HGF/c-Met signaling: Dihexa binds HGF with high affinity (reported K d ~65 pM in the original work) and is proposed to potentiate HGF dimerization and c-Met phosphorylation at subthreshold endogenous HGF concentrations

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EslamMSanyalAJGeorgeJInternational Consensus Panel

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