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Investigating therapeutic effects of indole derivatives targeting inflammation and oxidative stress in neurotoxin-induced cell and mouse models of Parkinsons disease

It plays a central role in oxidative-stress defense, phase II detoxification, and redox homeostasis

ALOX15 KD normalized the intracellular GSH ( P = 0.003), while chemical inhibition of 15LO1 had a marginal, but insignificant effect ( P = 0.066)

Treatment duration ranged from 4 weeks to 6 months (median 12 weeks) (Table 2)

The anti-oxidant and antitumor properties of plant polysaccharides