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3, 4, 5 Traditionally, mast cells and immunoglobulin E (IgE) have long been associated with the pathogenesis of immediate hypersensitivity reaction, the pathophysiologic hallmark of allergic rhinitis, allergic asthma, and anaphylaxis

mosquito and small rodents in the Caribbean areas, and the epizootic strains that are virulent to human and horse, found mainly in Venezuela, Colombia, and Peru, and circulate between several mosquito species and horses, which produce high-titered viremia sufficient to infect the vector mosquitoes

investigated the combined effects of hydrocaffeic, dihydroxyphenylacetic and hydroferulic acid metabolites from colon microbiota and found that these polyphenols can reduce the synthesis of prostaglandin E2 in IL-1-stimulated CCD-18 colon fibroblast cells [177]

10.1016/j.jep.2014.10.040 119 SeegerC.MasonW

In addition, Nrg4 restrains tumor-associated macrophage (TAM)-like macrophages and the exhaustion of cytotoxic CD8 + T cells to suppress NASH progression to liver cancer [83]

I., Almeida, A., Delgado-Esteban, M., Fernandez, E., & Bolanos, J