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Further cysteine-rich protein motifs that can be modified by electrophiles such as EdAG are the Zn-binding Cys 2 His 2 and Zn 2 /Cys 6 domains ( zinc finger ) of regulatory proteins such as nuclease enzymes, of DNA transcription factors and of metallothioineins [146,147]

Targeted PubMed searches yielded 14 high-quality references, including clinical trials and mechanistic studies, supplemented by 4 authoritative sources due to the niche nature of recent systematic reviews on copper peptide GHK-Cu

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Abnormal tau, mitochondrial dysfunction, impaired axonal transport of mitochondria, and synaptic deprivation in Alzheimers disease

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