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doi: 10.1016/S0959-8049(99)00133-1 256 GalimbertiVColeBFZurridaSVialeGLuiniAVeronesiPet al

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Furthermore, animal research has found that extremely high doses of alpha-lipoic acid may promote oxidation, alter liver enzymes, and place strain on liver and breast tissue (38, To date, very few studies have looked at the safety of alpha-lipoic acid in children and pregnant women

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Individuals who may be considered appropriate candidates include: Persistent fatigue or low energy despite adequate rest Frequent travel with dehydration, jet lag, or recovery issues High physical, cognitive, or professional stress levels Difficulty tolerating oral supplements or poor gastrointestinal absorption Need for hydration support under medical supervision Interest in supportive wellness care alongside doctor-guided treatments Each case is assessed individually