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No large-scale, long-term human trials exist to fully understand its safety profile
This is the case in health, but in disease, there are still some doubts about the role of the microbiota in the pathophysiology, namely, in the context of cancer, at both the organ and systemic levels

Investigating novel therapeutic strategies for GBM is both imperative and urgently required to address the limitations of current treatment modalities [8]

In addition, metabolic pathways produce free radicals, that can destroy carbohydrates, lipids, proteins, and nucleic acid

use glucose to synthesise bacterial cellulose, and this anabolic process involves sucrose, ethanol, and glycerol (Chawla et al., 2009