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Schimmer AD, Welsh K, Pinilla C, Wang Z, Krajewska M, Bonneau MJ et al
Ferreira Branquinho MS, Silva MBB, Castilho GA, Cavalcante J, Barros SBM, Clara RO et al (2022) Kynurenine inhibits melanogenesis in human melanocyte-keratinocyte co-cultures and in a reconstructed 3D skin model

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Combined inhibition of LDHB and SLC7A11 synergistically suppresses KRAS -mutant tumor growth by inducing ferroptosis in vivo We validated our in vitro findings in KRAS -mutant lung cancer xenografts and a genetically engineered mouse (GEM) model of autochthonous Kras G12D -induced lung adenocarcinoma that accurately resembles human disease [20]

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