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For example, it has been used in a murine colon cancer cell line (CT26) ( FIGURE 8 CARS CARS catalyzes the formation of cysteinyl aminoacyl-tRNA Cys (Cys-tRNA Cys ) through ATP-dependent activation of L-cysteine, yielding cysteinyl adenylate (Cys-AMP), followed by transfer of cysteine to the 3-terminus of tRNA Cys ( K m of E