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Neurological effects of high-dose idebenone in patients with Friedreich's ataxia: a randomised, placebo-controlled trial

[9] CoQ10 is a fat-soluble, vitamin-like coenzyme found naturally in every cell, with especially high levels in energy-intensive organs like the heart, liver, and kidneys

Moreover, dysregulation of AMP-activated protein kinase (AMPK), an energy sensor which is induced by energy depletion was also linked to ALS (reviewed in Perera and Turner, 2016)

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La translocacin de microorganismos y de toxinas urmicas producidas por la microbiota intestinal se asocia con una respuesta inflamatoria crnica, asocindose con mayor mortalidad, eventos cardiovasculares y alteraciones en el metabolismo mineral y seo