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Sinus tachycardia was observed during clinical studies of semaglutide injection for weight management

10.1002/advs.202504855 78 WeiC.LeiX.YuS

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Liraglutide also induction HO-1 expression by activating AMPK and promoting HIF-1 protein export from cytoplasm to nucleus, which significantly increases the expression of anti-apoptotic protein Bcl-2 and decreases the expression of pro-apoptotic Bax and Caspase-3 in HUVECs cells [134]