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The transcription factor Forkhead box O3a (FOXO3a) also regulates multiple antioxidant genes and is reduced in COPD lungs as a result of phosphoinositide-3-kinase (PI3K) activation [18,50]

AOD 9604 is a synthetic peptide fragment derived from the C-terminal region of human growth hormone and developed for research into metabolic regulation

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A second wave can also be observed in the later stage of AD with a positive correlation with amyloid load 375,376

Besides, if glutamine supplementation is conducted in patients with reduced glutaminolysis, pharmacokinetic studies including drug delivery route, dosage need to be further evaluated

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