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Description
Upon binding to its ligands, CD80 or CD86, CTLA-4 recruits phosphatases such as SHP-2 and protein phosphatase 2A (PP2A) to its cytoplasmic domain
A 5-year clinical outcome study on anti-BCMA CAR T-cell therapy in patients with relapsed/refractory multiple myeloma demonstrated significant efficacy and safety, providing important confidence and a reference point for the potential use of BCMA-targeted CAR T cells in the treatment of autoimmune diseases (114)
Hedin et al., 2014)
2022;23(12):e202100689
Ethics declarations Conflict of interest The authors declare that there has no conflict of interest
AA-NAT activity increases dramatically during darkness [1]
