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HA has been shown to modulate ocular surface inflammation through interactions with CD44 and other cell-surface receptors, thereby influencing leukocyte trafficking and reducing the expression of pro-inflammatory cytokines and chemokines (Wu et al., 2024)
Their functional enrichment analyses linked these genes to mRNA metabolic processes, immune cell regulation, and RNA transport pathways, confirming their potential role in OA pathogenesis and immune-mediated joint degradation (Huo et al., 2025)
Razi B, Imani D, Makoui M, Rezaei R, Aslani S
Adsorption of DNA and aptamers to sodium urate crystals and inhibition of crystal growth

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coli , thereby potentiating the killing effect of carbapenem