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Additionally, older adults who naturally have a more challenging time absorbing vitamin B12 or those on certain medications that affect B12 absorption may be ideal candidates

Vitamin B12 for Athletes: Dosing and Evidence (2026): The Short Answer Vitamin B12 (cobalamin) is essential for red blood cell production, oxygen delivery, and nerve function, all of which directly affect endurance performance

10.1089/acm.2006.12.881 Summary Keywords vitamin B12, efficacy, bioavailability, therapeutic approaches, meta-analysis, cobalamin Citation Mazur M, Ndokaj A, Salerno C, Vallone J, Ardan R, Bietolini S, Carrouel F, Wilk A, Sarig R, Ottolenghi L and Bourgeois D (2025) Efficacy of sublingual and oral vitamin B12 versus intramuscular administration: insights from a systematic review and meta-analysis