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To observe an immediate effect, after the piston removal a single intraperitoneal injection of either saline (5 mL/kg b.w.) or BPC 157 (2 g/kg b.w.) was administered at 10 min post-injury
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*Correspondence: Theerthankar Das, [email protected]
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doi: 10.1038/cdd.2009.49 21 EfferthT
Phase II detoxification binds these intermediates to molecules (like glutathione, sulfate, or methyl groups) so they can be safely excreted
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Ferritinophagy mediated by nuclear receptor coactivator 4 (NCOA4) is recognized as a major pathway for the activation of ferroptosis
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In an animal model, an MO extract helped prevent chemically-induced tumor formation by increasing glutathione activity (6)
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