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Central to the persistence of chronic infections is the role of the microbiome, a critical regulator of health and disease

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This suggests that these proteins may serve as valuable therapeutic targets

However, several recent studies demonstrate that hyperactivation of the Nrf2 signaling cascade favors the survival of both normal and malignant cells, protecting them against oxidative stress, and chemotherapeutic agents [40, 41]

doi: 10.1152/physrev.00045.2019
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[DOI] [PubMed] [Google Scholar] Ling, Y
