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Looking toward future research directions, attention should focus on long-term safety assessment of DPP1 inhibitors, biomarker development, optimal dosage determination, and combination treatment strategies

The result is a systems-level approach to digestive health, with butyrate at the center as the key metabolite.

Multi-agonist therapies combining GLP-1 with GIP or glucagon may amplify these benefits by improving fat metabolism and reducing cardiovascular risk even further

These wounds fail to progress through the normal healing phases and are characterized by a persistent inflammatory environment

Regulation of gamma-glutamyl-cysteine synthetase by nonallosteric feedback inhibition by glutathione

Activated neutrophils release ROS, proteases (e.g., neutrophil elastase), and neutrophil extracellular traps (NETs), contributing to tissue damage and mucus hypersecretion (105)