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For the nitrated octadecanoids, effects are also initiated from multiple interactions including those at nuclear receptors (e.g., Nrf2, PPARs, NFB, heat shock response, stimulator of interferon genes (STING)), and cellular receptors (e.g., angiotensin II type 1 receptors), as well as by direct modulation of enzyme activity (e.g., soluble epoxide hydrolase (sEH), 5-LOX, xanthine oxidase)

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Previous reports show that depleting GSH promotes ferroptosis in cancer cells harboring Ras mutations [13], which is consistent with our findings

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Assessment of the antioxidant effectiveness of alpha-lipoic acid in healthy men exposed to muscle-damaging exercise

Improved energy levels Mitochondria, the energy-producing powerhouses of cells, rely on glutathione for optimal function