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AOD-9604 was advanced through Phase I and Phase II clinical trials by Metabolic Pharmaceuticals between roughly 2003 and 2007 enrolling approximately 900 participants in total

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Vacuum perception may vary due to compound-specific lyophilization parameters, residual gas displacement, headspace volume, stopper elasticity, temperature or pressure fluctuations, and altitude changes during transport

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The vial should be kept out of reach of children, as with any medication

However, based on experience with similar medications, weight regains significantly within 6-12 months of stopping