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Johns wort with certain antidepressants or other drugs that affect serotonin (a substance produced by some nerve cells) may lead to increased serotonin-related side effects, which can be serious

[DOI] [PMC free article] [PubMed] [Google Scholar] 35.Sktar E, Ekinci D, Sktar E, Beydemir S, Glin I, Gnay M

About 90% of patients experience a prodromal phase (63), that is characterized mainly by signs and symptoms of autonomic dysfunction such as pallor, sweating, lethargy, hot flashes and rarely temperature change and drooling (65)

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doi:10.1007/s00415-012-6712-2 Jeong SH, Lee SU, Kim JS

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