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Most of these claims are based on anecdotes, not long-term human studies and these drugs can often come with long term side-effects

[DOI] [PMC free article] [PubMed] [Google Scholar] Sun L

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This mechanism involves NO attack of PDH-E2 associated lipoates

In January 2025, the supplemental Biologics License Application (sBLA) for intravenous (IV) maintenance dosing of the treatment was approved in the U.S
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