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The Framingham Heart Study and subsequent risk prediction models helped establish total cholesterol, HDL-C, blood pressure, smoking, diabetes, and age as major determinants of cardiovascular risk (Kannel et al., 1961

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J Biol Chem 277:1132111328 Alonso JR, Cardellach F, Lopez S, Casademont J, Miro O (2003) Carbon monoxide specifically inhibits cytochrome C oxidase of human mitochondrial respiratory chain

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