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Due to its high fat solubility, disulfiram and its metabolites are widely distributed in body fat tissue and readily cross the blood-brain barrier (Triscott et al., 2012)

10.3389/fimmu.2021.794770 Front

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[5] Mechanisms of Apoptosis The response to antigenic material and the presence of cytokines, hydroxyl radicals or other viruses can trigger the activation of nuclear factor kappaB (NF-kB)