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Ligand loaded SA sensors equilibrated in Kinetics buffer (ForteBio) to establish a baseline, were dipped into wells containing 2-fold dilutions of TP53 (Millipore Sigma Aldrich

We know that metformin is a very useful medication in type 2 diabetes, combating insulin resistance, and is recommended first-line in almost all national and international guidelines

Personalized supplementation strategies, tailored to individual phenotypic characteristics, genetic polymorphisms (e.g., SLC6A8 , CKM , GATM ), comorbid conditions, and lifestyle factors, are essential to optimize therapeutic outcomes while minimizing adverse effects

Exposure to microplastics may impact neurological health through multiple mechanisms, including metabolic disturbances, inflammatory responses, and neurodegenerative alterations

Transporter-selective pharmacological modulation Growing structural and functional insight into zinc transporters raises the possibility of developing small molecules that selectively modulate individual transporters or their regulators

Endothel Dysfunct - Old Concepts New Chall [Internet]