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Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse diet-induced obesity in mice. Nature Medicine, 25(11), 17611771

Scientists are particularly interested in its ability to influence pathways associated with nicotinamide N-methyltransferase (NNMT), an enzyme involved in metabolic regulation

Wellness clinic use: Often structured in 8-week cycles, followed by reassessment before continuing

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Evidence remains largely preclinical, with growing interest in translational applications for aging, metabolic disorders, and neurodegeneration

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