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9 Proof-of-concept treatments were tested on patient fibroblasts and Pfa1 cells, which were knocked out of endogenous GPX4 and transfected to overexpress human mScarlet-tagged GPX4 WT (red) or GPX4 R152H (blue)

S., Pescatore, S

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Assessment of efficacy, safety, and tolerability of 4-n-butylresorcinol 0.3% cream: an Indian multicentric study on melasma

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Upon activation, T lymphocytes exhibit increased expression of SLC7A5, leading to increased glutamine uptake