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51 For adults aged 18 years and older, chronic use of high-dose ibuprofen is not recommended due to lack of evidence
showed that a fasting mimicking diet, consisting in 3 days of fasting followed by 4 days of refeeding in MPTP PD mice, reshaped gut microbiota composition and attenuated neuroinflammation by decreasing IL-1 levels and increasing BDNF levels in the striatum, thus offering innovative perspectives for the treatment of PD ( 2.1.3 Prebiotics Prebiotics are primarily indigestible dietary fibers that improve hosts health by selectively promoting the development and/or function of some bacteria in the gut ( Bifidobacteria ( et al
Pettegrew et al
10.1016/j.lfs.2020.117458 3 AbdullahK
Uric acid sodium has a protective effect on indomethacin-induced intestinal cell changes through its antioxidant activity [2]
