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[DOI] [PMC free article] [PubMed] [Google Scholar] 200.Camoretti-Mercado B., Lockey R.F
Furthermore, GTP cyclohydrolase 1 (GCH1) can suppress ferroptosis via the generation of the radical-trapping antioxidant tetrahydrobiopterin (BH4) (56)
Oral supplementation is the general approach to provide additional dietary levels of vitamin E
doi:10.33963/v.phj.104575
Microglia play a crucial role in orchestrating this phenotypic shift: upon activation, they release inflammatory mediators such as IL-1, TNF- and C1q, which induce a pro-inflammatory reactive astrocyte phenotype (often termed A1-like or neurotoxic reactive state) (Zhao et al., 2024
Lindeboom RG, Supek F, Lehner B
