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455 Ferroptosis in Duchenne muscular dystrophy Duchenne muscular dystrophy (DMD) is an X-linked recessive disorder caused by mutations in dystrophin protein encoded by the DMD gene

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Treatment discontinuation occurred in 18% due to adverse event severity

The early pharmaceutical-development designation was PL 14736, and the proprietary name Bepecin was used in early Croatian work

Nonetheless, a mouse study where low-dose oral DFO was added to chow for 2 weeks showed decreased brain iron by 18% by MRI and decreased multiple major iron metabolism-related protein levels (Thorwald et al., 2025)

"Wang Quanzhang: The lawyer who simply vanished"