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Because of its potential to enhance metabolic efficiency and endurance, MOTS-c is on the WADA Prohibited List in category S4

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Immunofixation interference Furthermore, administered human IgG1, monoclonal antibodies can interfere with the detection of clonal IgG, molecules in the sera of MM patients, as measured by serum protein electrophoresis and/or immunofixation electrophoresis (IFE), owing to comigration in the assays [53]