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Tranexamic acid is the most promising of the three drugs to deliver whitening effects, but it also has the most potential for unwanted effects which include nausea, vomiting, palpitations and reduced menses in women

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However, clinical translation faces key challenges such as tumor heterogeneity, drug delivery efficiency, and complex resistance mechanisms

This is a technology that we have been pioneering for more than 20 years, said Jeon Woong Kang, Ph.D., research scientist with MITs Laser Biomedical Research Center and co-author of the study