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However, when the gr1 mutation is introduced into the cat2 background, in which intracellular H 2 O 2 places an increased load on regeneration of GSH, the resulting double mutants show a much exacerbated phenotype compared to cat2 (Mhamdi et al., 2010a)

10.1016/j.phymed.2022.154081

In addition, placental extracts also served as natural anti-oxidants as they contained superoxide dismutase, catalase and glutathione peroxidase which function in neutralizing free radicals, preventing cellular impairment and disease development [67]

NAC has anticoagulant and thrombolytic effects [2426]

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A aggregates have been diminished after EGCG treatment in APP transgenic animal models