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Using NADPH as an electron donor, it breaks the disulfide bond of GSSG and reduces it to two GSH molecules, thereby maintaining a high GSH/GSSG ratio within the cell

And so I think its very interesting to look at, lets say, a lot of these blue zones, where despite there being some controversy around birth records or incomplete data, we can pretty much say our living at least a little bit better combination of healthspan and lifespan in the average Westerner and see what theyre doing and what we can replicate, even in a modern, post-industrial, comfort-controlled environment where we might not wake up in the morning and have our job to be like, I dont know, hiking dwarf goats up the side of a mountain to go gather some water or something like that

Vet Clin North Am Sm Anim Pract 51:635651 Clark MH, Ferguson DC, Bunick D, Hoenig M (2013) Molecular and histological evidence of brown adipose tissue in adult cats

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Cell cultures Cortical neurons in primary culture were prepared from fetal Wistar rats (E16), seeded at 2.510 5 cells per cm 2 in 6- or 12-well plates previously coated with poly-D-lysine (15 g ml 1 ) in DMEM (Sigma, Madrid, Spain) supplemented with 10% (v/v) fetal calf serum (Roche Diagnostics, Heidelberg, Germany)

Contribution to oxidative stress and interorganellar signaling