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aeruginosa CzcS reduces Zn(II) sensing and substitution of the Asp ligands with Cys enables Co(II) detection in vivo [109,115]

These properties allow non-covalent interactions to occur with Lys10 and Lys12 in the N -terminal domain, which translates into a reduction of -Syn aggregation and the disassembling of preformed fibrils, presumably stimulating the formation of off-pathway oligomers [306]

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