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Once reconstituted, always store at 28C and do not freeze

Beyond standard cytokines, adipose tissue secretes specialized signaling proteins called adipokines, which regulate systemic inflammation, metabolism, and immune responses, thus contributing to HS development and progression [7, 8]

Visible body-composition changes usually develop over 812+ weeks when paired with nutrition, movement, and sleep optimization

Clinical trial data demonstrate that oral Wegovy (25 mg semaglutide) achieved a mean body weight reduction of 13.6% over approximately 15 months, compared with 2.2% in placebo recipients, showing efficacy comparable to injectable Wegovy

Long-term evaluation of the efficacy and safety of these adjunctive therapies is required to guide their use in individuals with type 1 diabetes
