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Regulacja genow dostarcza tym samym mozliwych ram wyjasniajacych efekty obserwowane na poziomie komorkowym w odniesieniu do kolagenu, elastyny i markerow komorek macierzystych

(2014) Fructose-1,6-bisphosphatase opposes renal carcinoma progression, Nature , 513 , 251-255, doi: Anderton, B., Camarda, R., Balakrishnan, S., Balakrishnan, A., Kohnz, R
For instance, we recently showed that remifentanil, a MOR selective agonist, produces a significant desensitization by 60% on the cAMP pathway after 10 min while at the same time desensitization of the MAP kinases ERK1/2 signaling pathway was not significantly affected (Nowoczyn et al., Two types of desensitization, homologous and heterologous, were described

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PMID: 32488657

The twilight of immunity: emerging concepts in aging of the immune system