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Once-weekly tirzepatide versus once-daily insulin degludec as add-on to metformin with or without SGLT2 inhibitors in patients with type 2 diabetes (SURPASS-3): a randomised, open-label, parallel-group, phase 3 trial
Earlier phase 2 trials tested different timing protocols, including 2 week escalations and faster progressions to higher doses
Findings from the preclinical study indicated that TRZ attenuates high-fat diet-induced cognitive impairment through modulation of different signaling pathways, including BDNF (Ma et al
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