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Nature 471 (7337): 235-9, 2011
observed TP53 mutations in 10/55 (18%) patients with low and intermediate-1 risk MDS carrying del(5q), which render them at higher risk for disease evolution to AML [527] Another investigation reported TP53 mutations in 17% of lower-risk MDS with isolated del(5q),associated with shorter survival [554]
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& Ho, Y
, Aliakbarlu, J
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