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When the peptide concentration is too high, even small doses become difficult to measure accurately

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An injectable treatment could make the issue worse and increase the risk of side effects

For species level estimations (described in 46 ) in the heatmap, most of the OTUs could not be resolved to the species level (100% identity and coverage on NCBIs nucleotide BLAST: using the 16S rRNA database), and are thus reported as the resultant genera from our 16S sequencing