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Ficlatuzumab has been demonstrated to interfere with stromal contributions to proliferation, migration, and invasion in a preclinical in vitro model of HNSCC, as well as epithelial to mesenchymal transition (EMT) [118]

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doi: 10.1007/s00330-019-06164-1 20 UenoMNakagawaTWuBOnoderaMHuangCLKusakaTet al

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You may alternate this cream with a hydroxy acid at opposite times of the day

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