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In addition, the use of valproic acid with or without other anticonvulsants may cause hepatotoxicity and increase plasma ammonia concentrations, leading to encephalopathy

Carnitine transporter mutations in Crohn's disease consists of missense mutation(s) in the gene coding plasma membrane transporter OCTN1 (SLC22A4) and/or mutation(s) in the promoter of the gene encoding OCTN2 (SLC22A5) [14, 35]

Koeth RA, Lam-Galvez BR, Kirsop J, et al

[56] demonstrated that L-propionylcarnitine (L-PC), a propionyl ester of L-carnitine, is able to prevent CyA-induced acute nephrotoxicity, reducing lipid peroxidation in the isolated and perfused rat kidney in vitro

L-karnitin je zkladem transportnho systmu, kter doprav molekuly mastnch kyselin na msto spotebovn energie, proto je zkladn podmnkou spalovn tuku

Organs with high energy demands, such as the heart and skeletal muscles, contain a significant concentration of mitochondria
