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Iron chelators (e.g., deferoxamine) are also under investigation to determine their potential role in reducing iron-driven oxidative stress, offering a promising avenue for psoriasis treatment (191, 195197)

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Additionally, several rare pathogenic variants in SCN9A have been identified in patients carrying small fiber neuropathy [92], further underscoring the critical involvement of this gene in potentiating the mechanism of neuropathic pain

153 Mer tyrosine kinase (MerTK) is an essential membrane protein in macrophages that participates in efferocytosis

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