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These findings suggested that busulfan can significantly induce ROS creation and reduce antioxidants, leading to oxidative stress and lipid peroxidation in testicular tissue, which, in turn, can result in germ cell death, spermatogenesis impairment, and infertility (49)

Discussion At the patients initial presentation two years prior, light brown pigmentation was noted on the labial aspect of the attached gingiva in the anterior mandibular region

Antibiotics are used to prevent or treat wound infections and pneumonia [32]

423,527,528 Enzymatic processes include ferroptosis and reactions catalyzed by lipoxygenases, cyclooxygenases, and cytochrome P450

In this article, we aim to review the management of HE, starting with the efficacy and limitations of traditional agents with a focus on the evidence supporting newer therapies in HE (Table 1)

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