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Description
AMPK-Mediated BECN1 Phosphorylation Promotes Ferroptosis by Directly Blocking System Xc(-) Activity
It exerts anti-inflammatory effects by inhibiting the gene expression of pro-inflammatory cytokines such as IL-1, IL-1, IL-6, and IL-12p35, downregulating the activity of inflammatory enzymes like iNOS and COX-2, and suppressing key factors in inflammation signaling pathways such as NF-B, FOXO3a, and SIRT1(Parvez et al., 2019)
Upon receptor binding, EPA and DHA form heterodimers with the retinoid X receptor (RXR) to activate peroxisome proliferator response elements (PPREs), enhancing fatty-acid oxidation and suppressing NF-B- and activator protein-1 (AP-1)-mediated cytokine transcription
Looking to boost your energy and enhance your overall well-being
Side effects are minimal and temporary
2010 May;68(5):1059-64
