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Hong F, Xu P, Zhai Y

Certain mitochondrial proteins involved in the biosynthesis of iron-sulfur clusters (ISCs), such as cysteine desulfurase NFS1, ISC proteins, CISD1, and CISD2, have been shown to negatively regulate ferroptosis by reducing the availability of Fe 2+ [32,33,34,35]

Side effects of antidepressants during long-term use in a naturalistic setting

Prdxs are divided into the subgroups Prdx1/AhpC, Prdx5, Prdx6, Tpx (thiol peroxidase), PrdxQ/BCP, and AhpE

Multiple Cell Death Pathways Drive PD Progression Programmed cell death (e.g., apoptosis, necroptosis, pyroptosis, ferroptosis) and non-programmed necrosis (energy collapse, calcium overload) synergize, with core mechanisms including mitochondrial dysfunction, oxidative stress, and endoplasmic reticulum stress (ERS), leading to ROS bursts, metabolic dysregulation, and disrupted calcium homeostasis

10.1007/s13555-014-0046-1 139 KumariS.PanditaD.PooniaN.LatherV