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Key takeaways: Methylene blue is a salt and dye with antioxidant, anti-inflammatory, antidepressant and analgesic properties

On published endpoints, Novo Nordisk's April 2024 Phase 3 readout in type 2 diabetes reported a 14.2% mean body-weight reduction at 68 weeks for CagriSema 2.4mg/2.4mg from a 101kg baseline, versus 10.2% for semaglutide 2.4mg alone [4]

Mancini SJ, Boyd D, Katwan OJ, Strembitska A, Almabrouk TA, Kennedy S, Palmer TM, Salt IP (2018) Canagliflozin Inhibits Interleukin-1-Stimulated Cytokine and Chemokine Secretion in Vascular Endothelial Cells by AMP-Activated Protein Kinase-Dependent and -Independent Mechanisms
10.1115/1.1835363 J

[DOI] [PubMed] [Google Scholar] 100.Wu C.-R., Tsai C.-W., Chang S.-W., Lin C.-Y., Huang L.-C., Tsai C.-W

Chd5 Regulates the Transcription Factor Six3 to Promote Neuronal Differentiation
